In the world’s highest city, a lack of oxygen ravages the body

Source: Science Magazine

ON A COLD, GRAY MORNING earlier this year, Ermilio Sucasaire, a gold miner, sat in a white plastic chair with a stack of papers and a pen in his hand. His inquisitive eyes scanned a large room where a group of scientists were performing tests on his colleagues. One fellow miner rode a bicycle, panting heavily, electrodes attached to his chest. Another man had taken off his dirty sweater and was lying on a wooden bed, covered with blankets; a European researcher pressed an instrument against his neck while peering at a laptop.

Sucasaire was next—after he had signed a consent form and filled out a long questionnaire about his health, life, work history, family, and drinking, smoking, and coca-chewing habits. "I'm looking forward to it," he said.

The scientists, led by physiologist and mountain enthusiast Samuel Vergès of the French biomedical research agency INSERM in Grenoble, had set up a makeshift lab here in the world's highest human settlement, a gold-mining boomtown at 5100 meters in southeastern Peru. An estimated 50,000 to 70,000 people live here, trying to make it—and, many hope, strike it rich—under brutal conditions. La Rinconada has no running water, no sewage system, and no garbage removal. It is heavily contaminated with mercury, which is used to extract the gold. Work in the unregulated mines is back-breaking and dangerous. Alcohol abuse, prostitution, and violence are common. Freezing temperatures and intense ultraviolet radiation add to the hardships.